About Us
About Sycamore Management Solutions
Rooted in Strategy. Grounded in Insight. Growing Through Impact.
Sycamore Management Solutions is a boutique life sciences Strategic Partner, founded on a simple belief: that science-driven organizations succeed not merely through innovation, but through strategic clarity and disciplined execution.
With over two decades of leadership in pharmaceutical R&D Project and Portfolio Strategy-execution, governance, and alliance management, Darlington Ebere launched Sycamore to help emerging and established biopharma companies bridge the gap between vision and realization, accelerating the journey from promising assets to tangible market and patient impact.
We specialize in early clinical development strategy, R&D portfolio and program management, and cross-functional operating frameworks that accelerate innovation while ensuring scientific and regulatory rigor.
We operate at the intersection of strategy, execution, and capital, bringing structure to complex development portfolios, optimizing cross-functional decision-making, and enabling data-driven growth for clients across the life-sciences ecosystem.
Our Leadership
Darlington Ebere, MBA
Founder & Managing Partner | Sycamore Management Solutions
Darlington Ebere is a biopharma strategy and execution leader with more than two decades of experience guiding R&D portfolios, clinical development strategy, and operational transformation across global pharmaceutical and biotech organizations.
Before founding Sycamore Management Solutions, Darlington held senior leadership roles at Rhodes Pharmaceuticals, where he built and led the Portfolio & Project Management Office, and at Catalent Pharma Solutions, where he managed large-scale client partnerships spanning late-stage development through commercialization. Earlier in his career, he contributed to cross-functional initiatives across the full drug development lifecycle, supporting teams in clinical, technical, and regulatory disciplines.
At Sycamore, Darlington helps life-science companies translate strategic intent into measurable execution, bridging scientific innovation, operational excellence, and organizational alignment. His expertise includes R&D portfolio governance, alliance management, and clinical program acceleration, all underpinned by a philosophy of clarity, accountability, and purposeful leadership.
Grounded in both strategy and execution, through Sycamore, Darlington partners with pharma executives / development teams, investors, and operational leaders to deliver strategic clarity, executional precision, and sustainable growth, empowering organizations to navigate complexity with confidence and impact.
Todd M. Delehant, Ph.D., RAC
Regulatory Affairs Strategist | Partner, Regulatory & Quality Advisory
Dr. Todd Delehant is a Regulatory Affairs and CMC strategist with over two decades of experience guiding IND, NDA, ANDA, and global technology transfer submissions across brand and generic pharmaceutical portfolios. A RAC-certified expert with a Ph.D. from Iowa State University, Todd has built a career at the intersection of science, compliance, and business strategy, helping organizations align development rigor with global regulatory expectations.
At Sycamore Management Solutions, Dr. Delehant partners with clients to deliver comprehensive regulatory and quality guidance across the product lifecycle – from development through commercialization. His expertise covers regulatory strategy and agency engagement planning, CMC documentation and submission management, GxP compliance advisory, and lifecycle management support.
Driven by precision and partnership, Todd helps clients navigate regulatory complexity with confidence, bridging scientific innovation and compliance discipline to enable faster, safer access to therapies worldwide.
Throughout his tenure at Rhodes Pharmaceuticals and Paddock Laboratories, Todd led more than 75 regulatory submissions spanning six countries, directed cross-functional CMC operations, and served as primary FDA and DEA liaison for complex product portfolios. He is widely recognized for his collaborative leadership style, pragmatic problem-solving, and ability to transform fractured teams into cohesive, high-performing regulatory functions.
Sycamore Management Solutions
Strategic. Grounded. Growth-Driven.
Deep Biopharma Expertise:
We combine technical, regulatory, and commercial perspectives.
Hands-On
Execution
Not just advice—we lead programs from strategy through delivery.
Investor-Savvy
We bridge the language of science with the expectations of capital markets.
Flexible
Engagements
From short-term fractional leadership to full portfolio transformations.